Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice
نویسندگان
چکیده
منابع مشابه
High expression of LMO2 in Hodgkin, Burkitt and germinal center diffuse large B cell lymphomas.
BACKGROUND AND AIM The LMO2 gene encodes a transcription factor that regulates key events in erythropoiesis, angiogenesis, and embryogenesis and is highly expressed at the most immature stages of lymphopoiesis. Its implication in Hodgkin lymphoma (HL), Burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL) is limited in the literature. MATERIAL AND METHODS An immunohistochemical stud...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2015
ISSN: 0887-6924,1476-5551
DOI: 10.1038/leu.2015.41